Speak to your GP or treatment team if you have any of these symptoms. Decreased bone mineral density (a measurement of bone strength),meaning thinner, weaker bones that are more likely to break. It’s usually diagnosed with a bone density scan (often called a DEXA scan). Always tell your doctor or nurse about any changes to your skin. They can give you advice and may prescribe creams or medicines to help. If you forget to take your tablet, take it as soon as you remember.
Your doctor will talk to you about this treatment and its possible side effects before you agree (consent) to have treatment. They will explain why you are having letrozole and how long you will take it for. We know that it is common to struggle with your mental health when you have cancer or care for someone with cancer.
It is, however, being increasingly used as a treatment by fertility specialists to aid the development of ovarian follicles. It may be recommended by your doctor as an alternative to Clomiphene or Tomixifen if you have polycystic ovarian syndrome (PCOS) and have not responded to clomiphene or https://popatorthodontics.com/the-top-5-trusted-sources-for-steroids-in-the-uk-a/ Tomoxifen. Any breast cancer treatment – drugs or surgery – that reduces oestrogen levels in the body can increase the risk of osteoporosis and fractures. Some breast cancer drugs that do not have an effect on oestrogen levels may also have a direct effect on bones and reduce their strength.
N2 – To investigate the efficacy of letrozole 2.5 mg and 10 mg used as primary neoadjuvant therapy for patients with locally advanced and large operable breast cancer. Results This trial recruited nearly 5,000 women who’d already had surgery and then 4 to 6 years of hormone therapy for early stage breast cancer. If your bones are already beginning to show signs of thinning or if you already have osteoporosis, you may be given another drug to increase bone density and strength.
There are a number of ways to help reduce or control hot flushes and sweats. Some women find it helpful to avoid or cut down on tea, coffee, nicotine and alcohol. Evening primrose oil has been reported to be helpful in reducing sweats but it does not work for all women and it is very expensive. There are a lot of calories in Evening Primrose Oil so it may be fattening in some women. Some women have found complementary therapies have helped, and your GP may be able to give you details about obtaining these on the NHS.
Thrombosis These therapies slightly increase the risk of thrombosis (although not as bad as tamoxifen) – particularly if there is any disease in the pelvis or lower abdomen. Regular exercise encourage the blood to be pumped through the veins and reduce the risk of it stagnating and clotting in the veins. Your doctor has recommended a medication called Femara as treatment for your breast cancer. This page provides extra information about your medicine, summarises possible side effects and methods to alleviate them. It can also be used as firsttreatment before or after breast cancer surgery.
The suggested cause of joint pain is the drop in circulating oestrogens by aromatase inhibition in postmenopausal women. Extended adjuvant treatment of early invasive breast cancer in postmenopausal women, who have received prior standard adjuvant tamoxifen therapy (5 years). Conclusion The research team concluded that having intermittent letrozole doesn’t reduce the risk of early stage breast cancer coming back.
This trial compared taking letrozole all the time with stopping and starting treatment. It was for women who had been through the menopause and had early breast cancer that has tested positive for hormone receptors. Cancer-related fatigue is extreme tiredness that doesn’t go away with rest or sleep. It’s a very common side effect of breast cancer treatment and may affect you physically and emotionally. If you think you have fatigue, tell your GP or treatment team.
Your specialist may suggest changing to a different aromatase inhibitor such as anastrozole or exemestane, or another hormone treatment, as some women get on better with a different drug. If you think you need dental treatment, talk to your cancer doctor or nurse. Always tell your dentist you are having cancer treatment. If this happens, tell your doctor so they can give you painkillers.
If the scans and blood tests show that you have responded well and ovulated in your first cycle, continue to take Letrozole in your next menstrual cycle. Please contact the fertility nurse for a further prescription of Letrozole on email You should not need further monitored scans. If you have not conceived after 6 months of treatment then you will be referred back you your consultant. Advanced breast cancer in post-menopausal women after other anti-oestrogen therapy has failed.